Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results	Reference
1*	J:69389 Ayadi A, Suelves M, Dolle P, Wasylyk B, Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev. 2001 Apr;102(1-2):205-8
1	J:145172 Benedito R, Trindade A, Hirashima M, Henrique D, da Costa LL, Rossant J, Gill PS, Duarte A, Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli. BMC Dev Biol. 2008;8:117
1	J:32219 Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A, Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996 Apr 4;380(6573):435-9
1*	J:53293 Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk MM, Zwijsen A, Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999 Apr;126(8):1631-42
1*	J:75937 Damert A, Miquerol L, Gertsenstein M, Risau W, Nagy A, Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation. Development. 2002 Apr;129(8):1881-92
1*	J:25542 Dumont DJ, Fong GH, Puri MC, Gradwohl G, Alitalo K, Breitman ML, Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn. 1995 May;203(1):80-92
1*	J:23134 Faust C, Schumacher A, Holdener B, Magnuson T, The eed mutation disrupts anterior mesoderm production in mice. Development. 1995 Feb;121(2):273-85
1	J:243177 Lania G, Ferrentino R, Baldini A, TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells. PLoS One. 2015;10(9):e0138525
1*	J:36300 Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W, Ullrich A, High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 1993 Mar 26;72(6):835-46
1*	J:45679 Peterson RS, Lim L, Ye H, Zhou H, Overdier DG, Costa RH, The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives. Mech Dev. 1997 Dec;69(1-2):53-69
1	J:199855 Tanaka SS, Nakane A, Yamaguchi YL, Terabayashi T, Abe T, Nakao K, Asashima M, Steiner KA, Tam PP, Nishinakamura R, Dullard/Ctdnep1 modulates WNT signalling activity for the formation of primordial germ cells in the mouse embryo. PLoS One. 2013;8(3):e57428
1	J:51542 Tomihara-Newberger C, Haub O, Lee HG, Soares V, Manova K, Lacy E, The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives. Dev Biol. 1998 Dec 1;204(1):34-54
1	J:86157 Umans L, Vermeire L, Francis A, Chang H, Huylebroeck D, Zwijsen A, Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse. Genesis. 2003 Sep;37(1):5-11
1*	J:65521 Urness LD, Sorensen LK, Li DY, Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000 Nov;26(3):328-31
1*	J:12605 Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J, flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development. 1993 Jun;118(2):489-98
1	J:70581 Zwijsen A, van Grunsven LA, Bosman EA, Collart C, Nelles L, Umans L, Van de Putte T, Wuytens G, Huylebroeck D, Verschueren K, Transforming growth factor beta signalling in vitro and in vivo: activin ligand-receptor interaction, Smad5 in vasculogenesis, and repression of target genes by the deltaEF1/ZEB-related SIP1 in the vertebrate embryo. Mol Cell Endocrinol. 2001 Jun 30;180(1-2):13-24